{"id":7705,"date":"2023-06-19T17:10:20","date_gmt":"2023-06-19T08:10:20","guid":{"rendered":"https:\/\/c-mng.cwh.hokudai.ac.jp\/lbd.eng\/Root\/?page_id=7705"},"modified":"2024-11-06T16:58:21","modified_gmt":"2024-11-06T07:58:21","slug":"projects","status":"publish","type":"page","link":"https:\/\/c-mng.cwh.hokudai.ac.jp\/lbd.eng\/Root\/research\/projects.html","title":{"rendered":"RESEARCH TOPICS\u3000\u7814\u7a76\u30c6\u30fc\u30de"},"content":{"rendered":"

Hard Tissue Biomechanics<\/h2>\n

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Cancellous stiffness with the microarchitecture of the trabecular network<\/h3>\n

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In osteoporosis, there are many fractures in areas where cancellous bone occupies a large proportion. Cancellous bone has a structure in which small beam-like bones called trabeculae are arranged in a three-dimensional structure. The strength of cancellous bone as a whole is less than one-tenth that of cortical bone and is known to depend on the trabecular structure. The relationship between the structural and mechanical properties have not yet been clarified. In this laboratory, we are researching the measurement method of mechanical properties from cancellous bone to trabecular level and the relationship between trabecular network structure and mechanical properties.<\/p>\n

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Biomimetic Material Design<\/h2>\n

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Biomimetically mineralized collagen matrix using PILP process<\/h3>\n

PILP\u30d7\u30ed\u30bb\u30b9\u306b\u3088\u308b\u9aa8\u6a21\u5023\u77f3\u7070\u5316\u30b3\u30e9\u30fc\u30b2\u30f3\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u306e\u5275\u88fd<\/h4>\n

Microscopically, bone is a composite structure consisting of inorganic mineral crystals and organic collagen molecules. In recent years, attempts have been made to develop artificial bone materials that mimic these microscopic composite structures. However, it has not been realized because the details are still unknown. Polymer-induced liquid precursor (PILP) process has attracted attention for the purpose of mineralization of such polymer matrix. According to this method, it is possible to easily generate calcified tissue derived from the polymer matrix structure, and it will contribute to the development of biomaterials that have a hierarchical structure similar to living bones and mechanical functions. In our laboratory, we are conducting research to clarify the relationship between structural and mechanical properties of mineralized bone-like materials fabricated by the PILP process.<\/p>\n

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Biomimetic porous structure by additive manufacturing<\/h3>\n

\u4ed8\u52a0\u88fd\u9020\u6cd5\u306b\u3088\u308b\u9aa8\u6a21\u5023\u591a\u5b54\u8cea\u6750\u6599\u306e\u4f5c\u88fd<\/h4>\n

Additive manufacturing is a new technology that has many advantages over conventional manufacturing technologies, such as weight reduction and high strength. In the medical field, application to the development of implants based on this technology is expected, and further improvements in performance and reliability are required. In our laboratory, we are conducting additive manufacturing experiments with a 3D printer and investigating the relationship between structural parameters and mechanical properties by mechanical tests of the fabricated porous structure.<\/p>\n

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Hard Tissue Biomechanics \u786c\u7d44\u7e54\u306e\u30d0\u30a4\u30aa\u30e1\u30ab\u30cb\u30af\u30b9 Cancellous stiffness with the microarchitecture of the trabecular networ […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":8,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/lbd.eng\/Root\/wp-json\/wp\/v2\/pages\/7705"}],"collection":[{"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/lbd.eng\/Root\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/lbd.eng\/Root\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/lbd.eng\/Root\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/lbd.eng\/Root\/wp-json\/wp\/v2\/comments?post=7705"}],"version-history":[{"count":49,"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/lbd.eng\/Root\/wp-json\/wp\/v2\/pages\/7705\/revisions"}],"predecessor-version":[{"id":8747,"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/lbd.eng\/Root\/wp-json\/wp\/v2\/pages\/7705\/revisions\/8747"}],"up":[{"embeddable":true,"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/lbd.eng\/Root\/wp-json\/wp\/v2\/pages\/8"}],"wp:attachment":[{"href":"https:\/\/c-mng.cwh.hokudai.ac.jp\/lbd.eng\/Root\/wp-json\/wp\/v2\/media?parent=7705"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}